M00000509
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ISO 21766:2021 Tobacco and tobacco products - Determination of tobacco-specific nitrosamines in tobacco products - Method using LC-MS/MS
standard by International Organization for Standardization, 02/01/2021
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Availability date: 2021-11-25
ISO 21766:2021 specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in tobacco and the following tobacco products: cigarettes, cigars and smokeless tobacco products using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The TSNAs determined with this method are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).